2020 and 2022 US Senate Election with President Biden-D and President Trump-R.

2020 - Democrats need a net gain of 4 seats to get back in the majority.
Democrats will hold onto:
1)MA(Markey-D/Kennedy-D)36
2)RI(Reed-D)37
3)NJ(Booker-D)38
4)DE(Coons-D)39
5)IL(Durbin-D)40
6)OR(Merkley-D)41
7)VA(Warner-D)42
8)NM(OPEN Udall-D/Lujan-D)43
9)MN(Smith-D)44
10)NH(Shaheen-D)45
11)MI(Peters-D)46
Democrats will pick up
1)CO(Gardner-R/Hickenlooper-D)47
2)AZ special(McSally-R/Kelly-D)48
3)NC(Tillis-R/Cunningham-D)49
4)ME(Collins-R/Gideon-D)50
5)GA special(Loeffler-R/Lieberman-D)51
2022 with Biden.
The most vulnerable Democratic held seats up in 2022
GA(Lieberman-D)
AZ(Kelly-D vs Ducey-R)
NH(Hassan-D vs Sununu-R)
Democrats will pick up
NC(OPEN Burr-R/Stein-D,)
PA(Toomey-R vs Shapiro-D)
WI(Johnson-R vs Kaul-D)