US Senate seats up for re-election in 2022 that will keep Democrats in the majority is GA,PA,or NV.

Democrats are favored to win.
37)HI(Schatz-D)
38)CA(Padilla-D)
39)MD(Van Hollen-D)
40)VT(Welch-D)
41)NY(Schumer-D)
42)OR(Wyden-D)
43)IL(Duckworth-D)
44)CT(Blumenthal-D)
45)WA(Murray-D)
46)CO(Bennet-D)
47)NH(Hassan-D)
48)AZ(Kelly-D)

Democrats will win GA(Warnock-D) on the 12/6/2022 runoff.
Democrats need to PA(Fetterman-D),NV(Cortez Masto-D) or both.

If Democrats win both PA and NV, they are officially in the majority. GA will not matter.
If Democrats win either PA or NV but not both, they need to win GA on the 12/6/2022 runoff.