The most vulnerable Republican held US Senate seats up in 2022 is PA,NC,and WI.

The most vulnerable Democratic held US Senate seats up in 2022 is GA,AZ,and NV.
Democrats will hold onto-
37)HI(Schatz-D)
38)NY(Schumer-D)
39)CA(Padilla-D)
40)VT(Welch-D)
41)MD(Van Hollen-D)
42)CT(Blumenthal-D)
43)OR(Wyden-D)
44)WA(Murray-D)
45)IL(Duckworth-D)
46)CO(Bennet-D)
47)NH(Hassan-D)
48)AZ(Kelly-D)
49)NV(Cortez Masto-D)
50)GA(Warnock-D)
51)PA(Fetterman-D or Lamb-D)
52)WI(Barnes-D)
53)NC(Beasley-D)
54)OH(Ryan-D)