Health
Related: About this forumWhy some don't get COVID-19 or have mild symptoms.
https://science.sciencemag.org/content/early/2020/08/04/science.abd3871Abstract
Many unknowns exist about human immune responses to the SARS-CoV-2 virus. SARS-CoV-2 reactive CD4+ T cells have been reported in unexposed individuals, suggesting pre-existing cross-reactive T cell memory in 20-50% of people. However, the source of those T cells has been speculative. Using human blood samples derived before the SARS-CoV-2 virus was discovered in 2019, we mapped 142 T cell epitopes across the SARS-CoV-2 genome to facilitate precise interrogation of the SARS-CoV-2-specific CD4+ T cell repertoire. We demonstrate a range of pre-existing memory CD4+ T cells that are cross-reactive with comparable affinity to SARS-CoV-2 and the common cold coronaviruses HCoV-OC43, HCoV-229E, HCoV-NL63, or HCoV-HKU1. Thus, variegated T cell memory to coronaviruses that cause the common cold may underlie at least some of the extensive heterogeneity observed in COVID-19 disease.
phylny
(8,554 posts)Baitball Blogger
(47,722 posts)of previous exposure to common colds. But, no one knows why or where they got that exposure.
phylny
(8,554 posts)Nay
(12,051 posts)exposure to certain specific cold viruses can stimulate a person's T-cells (cells that will 'remember' invading viruses and prompt a very quick bodily reaction to stop the invader) quickly enough that the person will have an asymptomatic response to COVID19 -- IOW, the virus gets beaten back before you get sick -- or the person will have only mild symptoms and then shake off the virus. They conclude by saying their results are still very speculative.
But I may be reading this incorrectly, so it's IMHO.
safeinOhio
(33,925 posts)Dr. fauci referred to it yesterday.
Nay
(12,051 posts)goes from "existing cold germ immunity" to "T-cells that attack COVID too." If they can find out exactly what is happening in all those steps, there's a good chance that they'll be able to develop a vaccine or shot that will at least keep a case of COVID from killing you or damaging you severely. Let's hope!
Response to safeinOhio (Original post)
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safeinOhio
(33,925 posts)Trying to keep up. I now wear a shield along with a mask. Looking more like aerosol spray may be more dangerous than any other way of spreading the virus. That along with load and speed has me trying that combination to stay safe. Cant hurt.
clarkd101
(15 posts)Thank you for the information.
safeinOhio
(33,925 posts)Best place on the internet for info. If you find something good, be sure to share it here.