Immune System Runs On 24 Hr Cycle- Vaccines May Work Better If Taken at Certain Times; 'Blue Light'

- The Body- Heart Immune System.
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The immune system runs on a schedule & vaccines may work better if you get them at certain times, Salon 6.12,.22. Ed.

- A new study finds the body's immune system operates on a 24-hour cycle — with implications for things like vaccines -

There are certain fixed rules that apply to all humans when it comes to how we sleep. We need our tracheas to stay open while we recline, lest we suffer apneas and struggle to breath during slumber. If we wake up to an annoying sound (such as those produced by certain alarm clocks), we'll be cranky during the day. And although it is possible to take catnaps during the daytime, our inclination is to want to sleep when it is night.

That last rule exists because we operate according to something known as a circadian rhythm, an internal clock that keeps most of our physiological processes operating along what amounts to a 24-hour cycle. This is why experts advise people against using electronic gadgets like cell phones before sleeping, as they produce light that convinces your brain it should be awake. Proper sleep hygiene and following your internal clock's circadian rhythms is essential to overall health — especially, as a recent paper in Science magazine underscores, when it comes to your immune system.

It all comes down to understanding the concept of the "immune rhythm." The basic idea behind the immune rhythm is that your immune system runs on a clock, akin to your circadian rhythm. And that can have health implications depending on what your immune system is expected to do at different times of day, as the paper explains.

- Researchers found that patients who were vaccinated earlier in the day tended to have a better immune response than those vaccinated in the afternoon or evening. -

"Immune rhythms were first found in the innate immune system in 1960, & 10 years later, components of the adaptive immune system were shown to be similarly time-of-day dependent," the authors write. "More than half a century later, we now know that immune cellularity, migration, & function are all regulated by the circadian clock." In the study, patients who were vaccinated earlier in the day tended to have a better immune response than those vaccinated in the afternoon or evening. Patients that received influenza vaccinations between 9 AM -11 AM had a higher antibody response than those who received the same shots between 3 PM- 5 PM. In the case of SARS-CoV-2 vaccinations, patients who received their shots at earlier hours had higher levels of neutralizing antibodies....
- More, https://www.salon.com/2022/06/12/immune-system-schedule-vaccines-study/
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- 'BLUE LIGHT' Has a Dark Side, Harvard Health, 2020. What is blue light? SCREENS. The effect blue light has on your sleep and more, https://www.health.harvard.edu/staying-healthy/blue-light-has-a-dark-side

Although it is environmentally friendly, blue light can affect your sleep and potentially cause disease. Until the advent of artificial lighting, the sun was the major source of lighting, & people spent their evenings in (relative) darkness. Now, in much of the world, evenings are illuminated, & we take our easy access to all those lumens pretty much for granted. But we may be paying a price for basking in all that light. At night, light throws the body's biological clock—the circadian rhythm—out of whack. Sleep suffers. Worse, research shows that it may contribute to the causation of cancer, diabetes, heart disease, & obesity.
- What is blue light? Not all colors of light have the same effect. Blue wavelengths—which are beneficial during daylight hours because they boost attention, reaction times, & mood—seem to be the most disruptive at night. And the proliferation of electronics with screens, as well as energy-efficient lighting, is increasing our exposure to blue wavelengths, especially after sundown. - Light and sleep...
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- NIH: Blue Light, Computer Screens. Eye Damage: Cornea, Cataracts, Retina, 2018,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288536/

Research progress about the effect and prevention of blue light on eyes. - Abstract: In recent years, people have become increasingly attentive to light pollution influences on their eyes. In the visible spectrum, short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration, even stimulating the brain, inhibiting melatonin secretion, and enhancing adrenocortical hormone production, which will destroy the hormonal balance and directly affect sleep quality.
Therefore, the effect of Blu-rays on ocular is becoming an important concern for the future. We describe blue light's effects on eye tissues, summarize the research on eye injury and its physical prevention and medical treatment...