Health
Related: About this forumMIT Researchers Make Discovery That Could Lead To The Reversal Of Alzheimer's Disease
Story by David Wetzel • 14h ago
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Neuroscientists at MIT have discovered a way to potentially reverse neurodegeneration and other issues related to Alzheimer's disease, according to a news release from the school.
Researchers, experimenting on mice, found that interfering with an enzyme that is typically overactive in the brains of people with Alzheimer's can reverse the degeneration in the brain.
The neuroscientists treated the mice with a peptide that successfully blocked the hyperactive version of enzyme CDK5 and found that it resulted in heavy reductions in the neurodegeneration and DNA damage taking place inside the brain. The experiment resulted in those mice improving in their ability to perform tasks such as navigating a water maze.
“We found that the effect of this peptide is just remarkable,” says Li-Huei Tsai, director of MIT’s Picower Institute for Learning and Memory and the senior author of the study. “We saw wonderful effects in terms of reducing neurodegeneration and neuroinflammatory responses, and even rescuing behavior deficits.”
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More at link. Knewz.
Link to story at MIT website.

ms liberty
(10,117 posts)Walleye
(39,259 posts)They didn’t even have a name for it back then, it was very difficult for my parents. I’m hopeful for this treatment
Raven123
(6,518 posts)Joinfortmill
(17,710 posts)rubbersole
(9,622 posts)Not only the patients, but their loved ones. Memory care facilities will always be needed. The people who work in them are angels.
stopdiggin
(13,544 posts)almost afraid to get my hopes up
(I've heard of almost nothing prior to this that actually talks about some 'reversal')
JudyM
(29,542 posts)This recent one was also promising, but reversal would be even greater:
https://www.sciencedaily.com/releases/2023/02/230206104118.htm
blue neen
(12,440 posts)It's so sorely needed.
calimary
(85,702 posts)Getting Grandma/Grandpa Back!
Even just the thought of it can be a real mood-lifter.
TeamProg
(6,630 posts)?t=71
Laura PourMeADrink
(42,770 posts)MLAA
(19,060 posts)Ziggysmom
(3,750 posts)and scientific research instead of weapons and war, what a great world this could be.
Abolishinist
(2,357 posts)Here's an idea... what if we worked on turning people into mice, as they seem to be at the forefront of medical technology.
keithbvadu2
(40,915 posts)I like the encouragement and possibilities but, many times, we have built up great expectations too early.
When it works itself out, all the better.
---------------------------------------------------
Example::: Many cures/treatments for COVID
Some by science, some by faith/wishful thinking/contrarianism.
https://democraticunderground.com/100215874832
NJCher
(39,550 posts)Why do you want me or anyone else to know about it?
Laura PourMeADrink
(42,770 posts)Phoenix61
(18,226 posts)path was where they were going to find a treatment and/or cure for Alzheimer’s.