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Disaffected

(5,025 posts)
Sat May 13, 2023, 10:40 PM May 2023

Anyone here take Repatha?

It's a relatively new LDL lowering drug, taken by subq injection either once or twice per month. Is typically taken with or without statins and without in particular if the patient cannot tolerate statins.

Anyhow, it works extremely well in reducing LDL but does have side effects. I have been taking it for a few months now but am concerned because I am getting chronic muscle pain, weakness and stiffness.

Was wondering if anyone else here was experiencing the same?

6 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
Anyone here take Repatha? (Original Post) Disaffected May 2023 OP
I've never used it, but... hippywife May 2023 #1
I have contacted my docs about it. Disaffected May 2023 #3
I don't take Repatha, but CoQ10 supplement helps me with the side effects you describe Captain Zero May 2023 #2
Thanks, I may try that again. Disaffected May 2023 #4
Many years ago I took timed released niacin, Guggul mushroom and red yeast rice Maraya1969 May 2023 #5
back in the day, I also took niacin. Disaffected May 2023 #6

hippywife

(22,767 posts)
1. I've never used it, but...
Sat May 13, 2023, 11:07 PM
May 2023

some years ago when my doctor put me on a med (don't remember what it was anymore) he specifically told me that if I experienced any of the symptoms you described in your OP, that I was to contact him ASAP!

Disaffected

(5,025 posts)
3. I have contacted my docs about it.
Sun May 14, 2023, 10:37 AM
May 2023

My GP said he doesn't know much about the drug and only recommended taking Tylenol. My Cardio doc, at my suggestion, had me get a blood test for creatine kinase (a product of muscle breakdown that both statins and Repatha can cause). The results were in the normal range so I guess that's not the issue.

And yes, as you imply, statins can cause a serious condition called rhabdomyolysis, a rare condition that causes muscle breakdown and, in the most severe cases, death. I had a second cousin die of the condition which is why I was particularly concerned about it.

Captain Zero

(7,473 posts)
2. I don't take Repatha, but CoQ10 supplement helps me with the side effects you describe
Sun May 14, 2023, 03:01 AM
May 2023

I take CoQ10 to help with those side effects that statins CAN have.

CHECK WITH YOUR DOCTOR.

Disaffected

(5,025 posts)
4. Thanks, I may try that again.
Sun May 14, 2023, 10:39 AM
May 2023

I originally tried Q10 when on statins but found it didn't seem do much for me. Maybe I'll try it again with the Repatha.

Maraya1969

(22,978 posts)
5. Many years ago I took timed released niacin, Guggul mushroom and red yeast rice
Sat May 27, 2023, 08:48 PM
May 2023

Everything went down amazingly.. I think the total cholesterol want down 75 points

Disaffected

(5,025 posts)
6. back in the day, I also took niacin.
Sun May 28, 2023, 10:39 AM
May 2023

LDL went down like a rock (I don't recall the numbers now) so much so that my endocrinologist, who was affiliated with a medical research centre, mused about doing a study on my case.

I have recently mentioned niacin to my cardio doc but she did not recommend it and it and it looks like it is not prescribed any more.

I do recall the rather severe flushing as a side effect - very uncomfortable.

Latest Discussions»Support Forums»Chronic Health Conditions Discussion and Support»Anyone here take Repatha?