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NH Ethylene

(31,021 posts)
4. A little detail about B.1.621
Fri Jul 30, 2021, 11:13 PM
Jul 2021

Katherine Laiton-Donato and colleagues in Colombia have now sequenced a new highly divergent variant, with mutations including Spike substitutions L249S and E484K.

These two substitutions are thought to be associated with immune escape. The presence of E484K is especially believed to be responsible for resisting antibodies from convalescent blood plasma. These two mutations are associated with the B.1.1.28 and B.1.351 lineages (the Brazilian and South African variants, respectively), two variants of concern.

https://www.news-medical.net/news/20210316/New-Colombian-SARS-CoV-2-lineage-shares-antibody-resistant-mutations-with-other-variants.aspx

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