Adverse Drug Reactions Overly Affect Women. The Reason Why Is Starting to Emerge [View all]

(from the "it took you long enough" files)

Biomedical research helps us understand the timeline of diseases and how we can treat them. In the past, most of it has been conducted on male cells and experimental animals, such as mice. It has been assumed the results from such "pre-clinical" research on males apply to females too.

Yet men and women experience disease differently. That includes how diseases develop, the length and severity of symptoms, and the effectiveness of treatment options.
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The US Food and Drug Administration (FDA) has already recommended dosage changes for women for some drugs (such as the sleep drug zolpidem). Additionally, weight-adjusted dosing for some antifungal drugs and antihypertensive drugs appears to work.

On the other hand, drug reactions are strongly linked to what the drug does in the body in women, and less so in men. There are also many documented differences in physiology between men and women that relate to how drugs are absorbed and cleared by the body, and not to body weight.

https://www.sciencealert.com/adverse-drug-reactions-overly-affect-women-the-reason-why-is-starting-to-emerge

Good discussion on how the study was desugned and if I lived another 100 years, I might live to see it penetrate the rock headed prejudice of drug researchers that women are not just small men.