Another Significant Advance with an Alzheimer's Drug [View all]

This is not the same one I posted about a few weeks ago. One of the experts quoted in the articles says "we are in a new era of disease modification for Alzheimer's disease."

This one is called "donanemab ." It is an antibody therapy that targets amyloid beta.There has, however, been two deaths attributed to side effects of this drug.

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'Remarkable' Alzheimer's drug reduces cognitive decline, study shows

US pharmaceutical giant Eli Lilly on Wednesday announced its experimental Alzheimer's drug significantly slowed cognitive and functional decline, results hailed as "remarkable" by experts despite some patients experiencing serious side effects.

In an analysis of nearly 1,200 people in the early stages of the disease, donanemab slowed the progression of symptoms by 35 percent over a period of 18 months compared to placebo.

This was measured by cognition and their ability to carry out daily tasks like managing finances, driving, engaging in hobbies and conversing about current events in a standardized index called the Integrated Alzheimer's Disease Rating Scale (iADRS).

Side effects included temporary swelling in parts of the brain, which occurred in almost a quarter of the treated patients, as well as microhemorrhages that occurred in 31 percent of patients on the treatment arm and 14 percent of patients in the placebo group.

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Link to story at Medical Expess.

Link to previous post on new dementia drug (mentioned in article).