I am one of the ones that the depression literally physically made me hurt. I think that is why the Lunesta commercial resonates with me so much. I don't take Lunesta, but I "get" the commercial where they say "depression hurts." I am on another medication, but it took many trial and error attempts with other antidepressants until I found the one that works for me. Before finding my certain medication that I take now, I could not love those butterflies in that commercial, even though I do love butterflies normally. Depression literally physically hurt. I felt it most in my chest. My heart and lungs are in good condition. The hurt came from the depression, not any other medical condition. I no longer feel that heavy, painful feeling in my chest and getting up out of bed is easier now. Although, I have to admit, my aches and pains from various injuries through the years (from my clumsiness) do make me make that stereotypical "old person" grunt sound when I get up out of bed or a chair, lol. But, at least I WANT to get out of bed now. I spent years so depressed that I did really want to get out of bed. I am so thankful I finally got the right diagnoes (plural) and my doctor helped me find the right medication for me. It has helped me make life better. It doesn't "cure" the depression, but it does give me better thought patterns than I used to have. I used to have negative thought patterns too.